Madrid went into halftime with a three-goal lead after Marco Asensio scored twice in three minutes and debutant Javi Sanchez also got on the scoresheet late in the half.
Barcelona and Paris St Germain claimed impressive victories at Manchester City and Bayer Leverkusen respectively in the first legs of their Champions League last 16 ties on Tuesday.
Images from the UEFA Champions League matches played on Tuesday night.
Nadal said his back was still bothering him against world number 56 Djere
Paris St Germain will play Borussia Dortmund and Barcelona were pitted against an unpredictable Napoli, while Chelsea were drawn against Bayern Munich. City, who will be at home in the second leg, have yet to beat the Spanish side with two draws and two defeats in their previous four meetings.
Arsenal will have another chance to beat Bayern Munich in a Champions League knockout tie after the sides were paired in the round of 16 following Monday's draw. The teams met in the knockout stages in 2005, 2013 and 2014 with the German champions winning on all three occasions. Bayern, who finished as runners-up in their group, will host the first leg.
IMAGES from the UEFA Champions League quarter-final played between Atletico Madrid and Leipzig on Thursday.
Real Madrid forward Cristiano Ronaldo ended his early-season drought in emphatic style when he hit five goals in a 6-0 romp at Espanyol on Saturday to become the club's record scorer in La Liga.
Victory in their first match on the league's resumption after the COVID-19 stoppage took basement team Espanyol to 23 points from 28 games, three points off the safety zone.
Arsenal fielded a strong team with Ozil installed as captain and the Premier League side soon took control against weakened opposition, given the time and space they will not be afforded when the domestic campaign kicks off in August.
Barcelona were so keen to bring Neymar back from Paris St Germain that the players were ready to accept delays to salary payments in order for the club to afford the Brazilian
There were, however, no eye-catching major deals in the final 24 hours of transfer activity for European clubs which continues the trend of recent January windows.
Barcelona manager Luis Enrique has labelled Lionel Messi has the 'best' player he has seen after the Argentine forward spurred a 2-0 victory over Ajax Amsterdam that secured the Spanish side a place in the Champions League knockout stages.
From Slam No 1 to Slam No 21 -- a summary of Nadal's 21 majors.
Arsenal have appointed former Paris St Germain coach Unai Emery as their new manager, the Spaniard succeeding the long-serving Arsene Wenger, the Premier League club announced on Wednesday.
News of all that's transpired on and off the football field
Aguero is expected to be the first of a number of arrivals at the Camp Nou this summer
Valverde refused to answer questions about the club's interest in Neymar and lamented the fact that the Spanish transfer window does not shut before the season starts, as it does in England.
Barcelona have signed centre back Samuel Umtiti from Olympique Lyon for 25 million euros ($27.75 million), the La Liga winners said on Tuesday.
United led through Juan Mata's 11th minute strike but just before halftime the visitors were level when De Gea weakly parried an Antonio Rudiger shot into the path of Marcos Alonso.
Marcus Rashford scored on his 100th Premier League appearance on Sunday to secure a 1-0 win over Leicester City that kept interim manager Ole Gunnar Solskjaer's dream start going at his old club.
Images from the UEFA Champions League matches played on Wednesday.
A round-up of Tuesday's action in the UEFA Champions League.
Lionel Messi scored his 650th goal for Barcelona while Antoine Griezmann struck the winner in a 2-1 home success over Athletic Bilbao
Images from the Champions League football matches played on Wednesday night.
Bale began Real's 3-1 win at Leganes on Wednesday on the bench, just as he had done against Real Sociedad and in their Champions League last-16 first leg against Paris St Germain.
Liverpool frustrated by 10-man Arsenal in League Cup semi stalemate
It was Novak Djokovic's first match this year after his Australian Open hopes were dashed when he was deported following an 11-day saga revolving around his decision not to have a COVID-19 vaccination.
There were a few nerves at the end but Liverpool set up a Champions League semi-final with Spain's Villarreal after Roberto Firmino scored twice in a 3-3 second-leg draw with Benfica on Wednesday to ensure a 6-4 aggregate win.
Barcelona forward Neymar has almost recovered from a foot injury and hopes to play in Saturday's Spanish league decider against Atletico Madrid, the Brazilian said in an internet chat with fans on Monday.
Images from Day 6 of the 2021 French Open at Roland Garros in Paris on Friday.
While Medvedev said he was "lucky" he felt better and could continue his match to advance, Spain's Paula Badosa gave up.
United are 16th in the standings with a game in hand heading into the international break.
Yet even without a transfer fee, Messi's colossal salary, reported to be the highest in world football, means very few clubs would be able to afford him.
Lionel Messi's fifth-place finish in this year's Ballon d'Or vote was absurd, Barcelona coach Ernesto Valverde said of the Spanish champions' Argentina forward on Tuesday.
PSG have set their sights on Messi, with PSG's players, coaches talking of their excitement about the prospect of bringing the Argentine to the French capital
Southampton's 15 million pound ($19.19 million) purchase of Lazio centre back Wesley Hoedt brought the overall spend by England's 20 elite clubs to a record 1.184.9 billion pounds.
Data revealed that Spain's La Liga and the Premier League were joint-top in terms of social media popularity, well ahead of the NBA, NFL and Serie A.
"It would be a big deal, increasing the team's appeal and also because it would bigger business for Juve, through merchandising," a Milan-based trader said.
Real Madrid targets, Paris St Germain coach Carlo Ancelotti and Malaga midfielder Isco, are close to joining the club, president Florentino Perez said on Monday.
